Young cannabis users have increased risk for MI-related hospitalization

  • Patel RS & al.
  • J Adolesc Health
  • 11.10.2019

  • von Emily Willingham, PhD
  • Clinical Essentials
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Takeaway

  • Adolescents and young adults who use cannabis have an increased risk for hospitalization for acute myocardial infarction (MI).

Why this matters

  • These authors say that clinicians need to be aware that cannabis use is climbing in this age group, and they should know the features of cannabis-associated MI.

Key results

  • Cannabis use was associated with 14.9% of MI hospitalizations in this study, which also looked at other substance use.
  • Cannabis use was associated with an increased risk for MI hospitalization (aOR, 1.362; P<.001>
  • Cannabis users had angioplasty more often than users of other drugs who had increased MI hospitalization.
  • The highest risk among the drug classes evaluated was for amphetamine users, as expected.
  • In-hospital mortality among cannabis users was 2%.

Study design

  • Retrospective analysis, data from the Nationwide Inpatient Sample (2010-2014), people ages 15-22 years with a diagnosis of acute MI (n=1694; 252 who had used cannabis).
  • These patients were compared with 9,465,255 inpatients without MI, with substance use included among potential risk factors.
  • Funding: None.

Limitations

  • Retrospective.
  • No causation established.