- Patients with vitiligo are at increased risk of several diseases, including multiple sclerosis, IBD, and lymphoma, according to a cross-sectional study.
Why this matters
- Few studies have investigated associations between vitiligo and other medical conditions; this study identifies a need for screening.
- Patients with vitiligo had higher prevalence of hypothyroidism (1.65-fold increase; P<.0001 multiple sclerosis increase p rheumatoid arthritis idiopathic thrombocytopenic purpura seronegative pernicious anemia myasthenia gravis ibd lymphoma and systemic lupus erythematosus>
- The most common disease was hypothyroidism (7.6% of patients).
- Black patients had the highest rate of comorbid autoimmune disease (16.4%), followed by white patients (16.3%), Hispanic patients (15.7%), South Asian patients (8.4%), and East Asian patients (7.9%).
- All statistically significant autoimmune disease associations were more prevalent in women compared with men.
- 1487 patients with vitiligo were analyzed for prevalence of comorbidities compared with the general population.
- Funding: None.
- Retrospective study design.