- Traumatic injury is associated with a more than 3-fold increased risk for chronic opioid use.
- Trauma patients who develop chronic opioid use had a significantly higher risk for death in the 6-18 months after their injury.
Why this matters
- Opioid use and associated risks are in the spotlight as clinicians and patients try to balance pain relief needs with risks.
- Study of 13,309 injured patients and 70,621 control individuals (age ≥15 years) from Sweden who were matched (1:5) for age, sex, and municipality; data collected during 2006-2015.
- Outcomes: chronic opioid use, all-cause mortality after opioid use.
- Funding: Karolinska Institutet; Swedish Society of Medicine.
- Traumatic injury was significantly associated with chronic opioid use:
- OR, 3.28 (P<.001>
- Chronic opioid use was significantly associated with increased mortality from any cause after 6-18 months of trauma:
- Adjusted HR, 1.82 (P<.001>
- Retrospective design.
- Results cannot be generalized.