- More than 60% of patients with lung cancer reported a cough severe enough to warrant treatment, with cough severity scores exceeding those reported in COPD or asthma.
Why this matters
- There is a lack of data on cough prevalence, severity, effect, clinical associations, causes, and treatment in patients with lung cancer.
- Longitudinal, observational study.
- 177 patients with lung cancer and cough.
- Funding: National Institute for Health Research; others.
- 62% reported that their cough was severe enough to warrant treatment; 52% classified their cough as grade 1, 47% grade 2, and 1% grade 3.
- Only 15% reported using antitussives at study onset.
- 36.2% of patients reported that cough began after lung cancer diagnosis.
- COPD, smoking history, and cancer characteristics (stage, histology, etc.) were not associated with cough severity or effect.
- On univariate analysis, reflux disease (P<.001 nausea and use of antitussives at study onset were significantly associated with cough severity remained days.>
- On univariate analysis, the use of opioids (P=.04) and antitussives (P<.001 were associated with improvement in cough severity at days.>
- Single-group, single-institution study.