- Patients with COPD who receive opioids for acute pain in the emergency department have a significantly higher risk for invasive ventilation, ICU admission, and death, according to study in medical centers in France and Canada.
Why this matters
- The prescription of nonpalliative opioids for patients with COPD increased significantly between 2008 and 2014.
- Study of 7799 patients (ages >40 years) with COPD who visited an emergency department during 2008 and 2014.
- Outcomes: invasive ventilation and death.
- Funding: Agir pour les maladies chroniques; E-health and trajectories medicine.
- Overall, 16.9% of patients were prescribed opioid drug.
- Opioid prescriptions were significantly increased during study period (13.8% to 22.2%; P<.01>
- Opioid administration to patients with COPD significantly (P
- Invasive ventilation: 3.41.
- ICU admission: 1.81.
- Death: 5.09.
- Spirometric/radiological tests were not conducted for COPD diagnosis.