Negative pressure wound therapy may improve burn healing in children

  • Frear CC & al.
  • Br J Surg
  • 14.09.2020

  • von Brian Richardson, PhD
  • Clinical Essentials
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Takeaway

  • Negative pressure wound therapy (NPWT) is associated with faster time to wound closure in children with small thermal burns.

Why this matters

  • This study helps clarify the efficacy of NPWT in the management of burns.

Key results

  • Median time to re-epithelialization was 8 days in patients treated with NPWT and 10 days in control participants.
  • NPWT was associated with a 22% improvement in expected time to wound closure in multivariate analysis (incidence rate ratio, 0.78; P=.005).
  • NPWT was also associated with a 60% reduced risk for referral for scar management (relative risk, 0.40; P=.013).
  • NPWT was associated with a “moderate” treatment burden (10 patients discontinued early).

Study design

  • 114 children with acute thermal burns covering
  • Funding: Australian Government Research Training Scholarship; Smith & Nephew.

Limitations

  • Small patient numbers.
  • Relatively long intervals between visits limited the precision of re-epithelialization assessments.