- Patients with hidradenitis suppurativa (HS) have higher odds of depression, anxiety, and suicidality, according to a systematic review and meta-analysis.
Why this matters
- Studies examining the relationship between HS and depression/anxiety have shown conflicting results.
- Patients with HS had increased prevalence and odds of:
- Depression: 26.5% vs 6.6% (OR, 2.54; P<.001>
- Anxiety: 18.1% vs 7.1% (OR, 2.00; P<.001>
- Used self-report or physician diagnosis: 1.82 (1.51-2.19).
- Used medical record review: 2.69 (2.23-3.24).
- Were cross-sectional: 2.05 (1.79-2.36).
- Included healthy control individuals: 2.62 (2.19-3.13).
- Used self-report or physician diagnosis: 1.67 (1.37-2.05).
- Used medical record review: 2.13 (1.70-2.66).
- Included healthy control individuals: 2.03 (1.59-2.60).
- Used other dermatologic disorders as control individuals: 2.05 (1.88-2.22).
- 27 studies identified by systematic review were included in the meta-analysis.
- Funding: None disclosed.
- Individual patient data not available.