Lung cancer: is hoarseness common after resection with SLND?

  • Sano Y & al.
  • Eur J Cardiothorac Surg
  • 13.07.2018

  • von Kelli Whitlock Burton
  • Univadis Clinical Summaries
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Takeaway

  • 6% of patients who underwent radical resection for lung cancer combined with systematic lymph-node dissection (SLND) developed hoarseness after surgery.
  • Patients with hoarseness and right recurrent laryngeal nerve (RLN) improved on their own while those with left RLN did not.

Why this matters

  • Although hoarseness is a known complication after upper mediastinal SLND for NSCLC, data on the long-term outcome of RLN paralysis are lacking.

Study design

  • 248 patients underwent resection for lung cancer with mediastinal SLND.
  • Funding: None disclosed.

Key results

  • 22 patients developed hoarseness.
  • Hoarseness developed after right upper lobectomy in 4.3% of patients, after right middle lobectomy in 14.3%, after right lower lobectomy in 4.8%, after left upper lobectomy in 19.0%, and after left lower lobectomy in 7.7%.
  • 21 patients with hoarseness underwent laryngoscopy, and among these 23.8% had right RLN paralysis and 71.4% had left RLN paralysis.
  • 16 patients (72.7%) who had right RLN recovered without treatment in an average of 10.4 months after surgery.
  • All 6 patients whose hoarseness did not improve had left RLN.

Limitations

  • Retrospective, single-center study.