Takeaway
- 6% of patients who underwent radical resection for lung cancer combined with systematic lymph-node dissection (SLND) developed hoarseness after surgery.
- Patients with hoarseness and right recurrent laryngeal nerve (RLN) improved on their own while those with left RLN did not.
Why this matters
- Although hoarseness is a known complication after upper mediastinal SLND for NSCLC, data on the long-term outcome of RLN paralysis are lacking.
Study design
- 248 patients underwent resection for lung cancer with mediastinal SLND.
- Funding: None disclosed.
Key results
- 22 patients developed hoarseness.
- Hoarseness developed after right upper lobectomy in 4.3% of patients, after right middle lobectomy in 14.3%, after right lower lobectomy in 4.8%, after left upper lobectomy in 19.0%, and after left lower lobectomy in 7.7%.
- 21 patients with hoarseness underwent laryngoscopy, and among these 23.8% had right RLN paralysis and 71.4% had left RLN paralysis.
- 16 patients (72.7%) who had right RLN recovered without treatment in an average of 10.4 months after surgery.
- All 6 patients whose hoarseness did not improve had left RLN.
Limitations
- Retrospective, single-center study.
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