- After parathyroidectomy for primary hyperparathyroidism, intraoperative parathyroid hormone (IOPTH) levels ≤40 pg/mL are associated with lower persistence rates compared with the traditional measure of ≥50% reduction.
Why this matters
- The optimal criteria for using IOPTH levels to predict normocalcemia are unclear.
- 2.5% of patients experienced persistent hyperparathyroidism after surgery.
- Patients with
- Patients with IOPTH >65 pg/mL had a higher persistence rate than patients with IOPTH
- Patients with IOPTH 40-65 pg/mL had a higher persistence rate than patients with IOPTH ≤40 pg/mL (3.4% vs 1.2%; OR, 4.2; P<.001>
- 2654 patients with primary hyperparathyroidism who underwent parathyroidectomy were analyzed for associations between IOPTH and persistence rates.
- Funding: None disclosed.
- Retrospective study.