High BMI is tied to risk for early HF in younger women

  • Björck L & al.
  • Eur J Prev Cardiol
  • 05.11.2019

  • von Emily Willingham, PhD
  • Clinical Essentials
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Takeaway

  • Compared with having a normal BMI, values starting at high-normal and greater are tied to increased risk for early heart failure (HF) in young women.
  • Risk increase is 5-fold with BMI at or over 35 kg/m2.

Why this matters

  • In Sweden, where this study was conducted, HF rates are increasing in the younger population.
  • Increasing BMI is a global issue.

Key results

  • Vs BMI 20-2, risks (adjusted HRs, 95% CIs) for HF by BMI (kg/m2) were:
    • 22.5-
    • 25-
    • 27.5-
    • 30-
    • ≥35: 4.51 (3.63-5.61).
  • With further adjustments, HRs for HF associated specifically with coronary heart disease, diabetes, or hypertension increased even more with BMI in overweight and obese ranges.

Study design

  • Prospective, registry-based cohort study with 1,374,031 women, aged 18-45 (mean 27.9 [standard deviation, 4.9]) years, who delivered a child, 1982-2014.
  • Maximum follow-up was 33 years.
  • Mean age at HF diagnosis was
  • Mean BMI, 23.7 kg/m2, and 68.5% had normal BMI.
  • Funding: Swedish Heart and Lung Foundation; others.

Limitations

  • Some comorbidities were self-reported.
  • Follow-up data on weight lacking.