- In a large US cohort (n=135,794) of younger patients (age
- Social disparities related to risk were identified.
Why this matters
- Little is known about COVID-19 epidemiology in younger US patients.
- Social disparities seem to be present across age groups.
- SARS-CoV-2 testing was routinely performed on all admissions to PEDSnet, a network of 7 US health systems serving 6.5 million patients in 11 states.
- From January 1 to September 8, 2020, there were 135,794 patients age
- Funding: Patient-Centered Outcomes Research Institute.
- Of the 135,794 patients, 4% tested positive.
- COVID-19 in 7% of positive patients met a broad definition of severe illness.
- The case fatality rate was 0.2%.
- Risk factors associated with infection included increasing age, having coverage by a public payer, and being Hispanic, Black, or of Asian ancestry.
- Despite lower rates of testing vs Whites, positive test results were more likely (aORs; 95% CIs) for patients who were:
- Black: 2.66 (2.43-2.90).
- Hispanic: 3.75 (3.39-4.15).
- Of Asian ancestry: 2.04 (1.69-2.48).
- Positive test results were more likely observed with a variety of conditions, including cardiac, endocrinological, genetic, and metabolic disorders (using standardized ratios).
- Electronic health records were used.
- Retrospective, observational design.