Cochrane: exercise boosts exercise capacity, QoL in advanced lung cancer

  • Peddle-McIntyre CJ & al.
  • Cochrane Database Syst Rev
  • 11.02.2019

  • von Kelli Whitlock Burton
  • Studien – kurz & knapp
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Takeaway

  • Exercise training was associated with improved fitness and cancer-specific QoL in patients with advanced lung cancer.

Why this matters

  • Data on the benefits of exercise training in patients with advanced lung cancer were lacking.

Study design

  • Cochrane meta-analysis of 6 randomized controlled trials comparing exercise with no exercise in a total of 221 patients with lung cancer.
  • Funding: None disclosed.

Key results

  • The exercise group had significantly better 6-minute walk distance (6MWD; mean difference, 63.33 m; 95% CI, 3.70-122.96) and disease-specific QoL (standardized mean difference, 0.51; 95% CI, 0.08-0.93).
  • No difference between groups in physical functioning QoL, dyspnea, fatigue, anxiety or depression, lung function, performance status, or OS.
  • No serious adverse events reported in exercise group.

Limitations

  • Few studies with small sample size.
  • No comparison data on benefits of different types of exercise.