- Heavy use of medical marijuana in patients with chronic pain was associated with greater pain severity than light use.
Why this matters
- The findings point to the need for cannabis use guidelines designed to promote harm reduction.
- Study identified 989 daily users of cannabis (medical use only, n=531; medical+recreational use, n=458) for chronic pain.
- Funding: None.
- Subgroups based on cannabis use/day:
- light (1-2/day; n=307),
- moderate (3-4/day; n=382), and
- heavy (≥5/day; n=300).
- Lower pain severity was noted among light vs moderate and heavy cannabis users (P=.044).
- Lower pain interference (P=.024), positive affect (P=.039), and negative affect (P=.008) were noted in light vs heavy users.
- Low tetrahydrocannabinol and high cannabidiol products were preferred by 44.7% of light users vs 29.0% of moderate users and 12.4% of heavy users.
- Among medical-only participants, light cannabis users (vs moderate and heavy users, respectively; P<.0001 reported lower: style="list-style-type:circle;">
- pain severity (5.4 vs 6.2 and 6.2) and
- pain interference (4.4 vs 5.4 and 5.5).
- Cross-sectional study.
Coauthored with Chitra Ravi, MPharm