CDC: only 1/3 of pregnant women report having both influenza, Tdap vaccinations

  • Lindley MC et al
  • MMWR
  • 09.10.2019

  • von Liz Scherer
  • Clinical Essentials
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Takeaway

  • National surveillance data continue to show high rates of both influenza-related hospitalizations in pregnant women and pertussis-related deaths in infants aged 

Why this matters

  • Physicians should initiate maternal vaccination schedules early in pregnancy to improve influenza, tetanus-diphtheria-acellular pertussis (Tdap) vaccine discussion frequency.
  • Physicians should consistently offer influenza, Tdap vaccines to pregnant patients, highlighting infant protection benefits.

Key results

  • Pregnant women accounted for 24%-34% of 2341 reported influenza-related seasonal hospitalizations from 2010-2011 to 2017-2018.
  • From 2010 to 2017: 7731 infant pertussis hospitalizations, of which 50.8% (3928) occurred in infants aged
  • Internet panel survey: 53.7% (2097), 54.9% (817) of eligible pregnant women reported receipt of influenza, Tdap vaccines, respectively.
  • 34.8% of women with recent live births reported receipt of both.
  • 65.7%, 70.5% receiving a provider influenza or Tdap vaccination offer/referral, respectively, received either vaccine.
  • Reasons for nonreceipt: ineffective (17.6%, influenza), not knowing it was needed (37.9%, Tdap), infant safety risks (15.9%, 17.1%, influenza, Tdap, respectively).

Study design

  • Retrospective national surveillance and survey data analysis evaluating influenza and pertussis disease burden among pregnant women and infants, maternal influenza, and Tdap vaccination coverage.
  • Funding: CDC.

Limitations

  • Underestimated outcomes, under-/overestimated coverage.
  • Potential confounders unanalyzed.