A cohort study to examine the association between use of e-cigarettes and self-reported wheezing in adolescents found that e-cigarette use alone might not be associated with increased odds of wheezing, according to a study published in JAMA Network Open.
The analysis included data from 7,049 adolescents without asthma. The outcome measures were self-reported wheezing in the past 12 months (yes or no) and e-cigarette use (no use in the past year or never used, use in the past year, use in past 30 days, and use in past seven days). Survey-weighted logistic regression models adjusted for demographic characteristics and other risk factors were used.
In unadjusted models, the odds of wheezing in the past 12 months were higher for youths who had used e-cigarettes in the past year compared with those who had not. However, after controlling for the variables of race/ethnicity, household rules about the use of tobacco, contact with a smoker in the previous seven days, and current use of combustible tobacco products, the association of e-cigarette use with wheezing was not significant.
The findings suggest that other risk factors, including second-hand smoke exposure, may be associated with the development of negative respiratory symptoms among adolescents, the authors say.