Another case of SARS-CoV-2 reinfection has been reported, this time by clinicians in The Netherlands.
Reports of SARS-CoV-2 reinfection have been growing of late, with cases documented in various regions including Belgium, Ecuador, Hong Kong and the US.
In the journal Clinical Infectious Diseases, a Dutch team present the case of an 89-year old Dutch woman, suffering from Waldenström’s macroglobulinaemia, treated with B-cell-depleting therapy.
She presented to the emergency department with fever and severe cough, with a lymphocyte count of 0.4x109/L.
An in-house SARS-CoV-2 RT-qPCR test on a nasopharyngeal swab was positive. She was discharged after five days and besides some persisting fatigue, her symptoms had completely subsided.
Two days after a new chemotherapy treatment, 59 days after the start of the first COVID-19 episode, the patient developed fever, cough, and dyspnoea. At admission, her oxygen saturation was 90% with a respiratory rate of 40/min. SARS-CoV-2 RT-qPCR testing was positive. She tested negative for SARS-CoV-2 antibodies on days 4 and 6. On day 8, the patient deteriorated. She died two weeks later.
The case shows we still have a lot to learn about SARS-CoV-2.